Szajewska H, Kołodziej M, Łukasik J. Drug development and acute gastrointestinal infections. Expert Opin Investig Drugs. 2017 Dec 26:1-6
Clarifying the role of intestinal mucus in reducing inflammation and infection has led to the development of ‘mucosal protectors’. These agents form a bioprotective film in the gastrointestinal tract and potentially may prevent microorganisms from crossing the mucus barrier . To date, the best studied substances include xyloglucan (a hemicellulose polysaccharide found in all land plants) and gelatin tannate (a complex of tannic acid, which possesses astringent, antibacterial, and anti-inflammatory properties, and is a protective gelatin). However, data on the efficacy of these two agents are very preliminary.
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