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Barrier Technology

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Barrier dysfunction in the nasal allergy

Ayumi Fukuoka, Tomohiro Yoshimoto

In this review, the authors describe the importance of the epithelial barrier and the relationship between TJ disruption and allergic diseases. In addition, they discuss new findings regarding the association of TJ disruption and exacerbation of allergic rhinitis induced by diesel exhaust particles. As a main conclusion the authors highlight that the protection of the epithelial barrier function might prevent or inhibit the development or exacerbation of allergic rhinitis.

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Antibiotic-Resistant Infection Treatment Costs Have Doubled Since 2002, Now Exceeding $2 Billion Annually.

Thorpe KE, Joski P, Johnston KJ.

Kenneth Thorpe, from Emery University in Atlanta, and his colleagues found in a study carried out in the USA, that while the overall number of bacterial infections remained relatively constant between 2002 and 2014, rising from 13.5 million to 14.3 million annually, the proportion that were antibiotic-resistant rose dramatically, from 5.2% to 11.0%. Patients with antibiotic-resistant infections had spending for bacterial infection that was 165 percent higher than spending by patients without such infections. Sixty-one percent of antibiotic-resistant infections were associated with urinary tract infections. Their conclusion is that the direct costs and the mortality and morbidity attributable to antibiotic-resistant infections make a compelling case for urgent action by national and international policy makers.

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Xyloglucan, a Plant Polymer with Barrier Protective Properties over the Mucous Membranes: An Overview

Núria Piqué, María del Carmen Gómez-Guillén and María Pilar Montero

Disruption of the epithelial barrier function has been recently associated with a variety of diseases, mainly at intestinal level, but also affecting the respiratory epithelium and other mucosal barriers. Non-pharmacological approaches such as xyloglucan, with demonstrated protective barrier properties, are proposed as new alternatives for the management of a wide range of diseases, for which mucosal disruption and, particularly, tight junction alterations, is a common characteristic.

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Let's meet in..

2018, May 26

EAACI 2018

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2018, May 28

PharmaVenue May 2018

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2018, Jun 11

EuroPLX 67

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2018, Aug 29

FNM 2018

FNM-2018-Amsterdam
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2018, Oct 24

UEG Week 2018

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