New article in NEJM supports the role of increased intestinal permeability in the pathophysiology of IBS.
Increased intestinal permeability and tight junctions alterations trigger an inflammatory reaction which alters visceral neuromuscular function, leading to IBS symptoms like abdominal pain and diarrhea or constipation.
Ford et al. N Engl J Med 2017; 376:2566-78 - http://www.nejm.org/doi/10.1056/NEJMra1607547
Gelsectan® is a mucoprotector with components of natural origin, that reinforces the mucosa against pathologic aggression and helps restore its normal function, thus contributing to improve IBS symptoms.
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