Irritable Bowel Syndrome

Ford et al. N Engl J Med 2017; 376:2566-78 New article in NEJM supports the role of increased intestinal permeability in the pathophysiology of IBS.  Increased intestinal permeability and tight junctions alterations trigger an inflammatory reaction which alters visceral neuromuscular function, leading to IBS symptoms like abdominal pain and diarrhea [...]

Read More

Noventure’s participation to 2017 EAU

European Association of Urology – London 25th – 27th March 2017. More than 10.300 total participants, coming from 113 countries all over the world. Out of around 10.000 delegates, mainly urologists, nearly 20% were residents. 200 exhibitors took part to the congress, thus adding  further 2200 participants to the event. [...]

Read More

Corporate Press Release: Noventure and RFSU enter into agreement to commercialize Utipro® Plus across Nordic countries.

Barcelona, March 13, 2017 – Noventure and Riksförbundet för sexuell upplysning (RFSU), the Swedish Association for Sexuality Education, announce today that they have entered into an agreement by which RFSU will distribute Noventure’s Utipro® Plus in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden). With this agreement, Utipro Plus [...]

Read More

Effect of Utipro® (containing xyloglucan-gelatin) against Escherichia coli invasion of intestinal epithelial cells: results of an in vitro study.

De  Servi B et al. Future Microbiology. Published on line: 29 March 2016 Aim: To evaluate whether Utipro(®), a natural product approved to prevent urinary tract infections, protects intestinal epithelial cells from Escherichia coli adherence/intracellular invasion in vitro. Materials & Methods:  Caco-2 and CacoGoblet(TM) cells were treated with Utipro (1.5 [...]

Read More

Undissociated Gelatine Tannate reduces intestinal leakiness and mucosa inflammation by forming a protective biofilm: results from in-vitro and in-vivo studies.

L. Bueno et al. UEG Journal – United European Gastroenterology Journal, Oct.2013: Vol. 1, Supl. 1; ISSN 2050-6406 (print) ISSN 2050-6414 (online) – Pags A75-A76  Introduction: Gelatine (GEL) stabilised by cross-linking with tannic acid (TA) forms gelatine tannate (GT). GT is approved as medical device for the oral treatment of diarrhoea [...]

Read More

New insights into the mechanism of action of gelatine tannate for acute diarrhoea. Part 1: film-forming effect.

Freli V. et al. Presented at GFHGHP 2012. Presented as oral communication at the 33rd edition of the Congress from the Groupe Francophone d’Hépato-Gastroentérologie et Nutrition Pédiatriques in Nantes, France, March 2012. Abstract: New insights into the mechanism of action of gelatine tannate for acute diarrhoea. Part 1: filmforming effect. [...]

Read More

Intestinal goblet cells and mucins in health and disease: recent insights and progress.

Kim YS, Ho SB. Curr Gastroenterol Rep. 2010 Oct;12(5):319-30   The mucus layer coating the gastrointestinal tract is the front line of innate host defense, largely because of the secretory products of intestinal goblet cells. Goblet cells synthesize secretory mucin glycoproteins (MUC2) and bioactive molecules such as epithelial membrane-bound mucins (MUC1, [...]

Read More