Olive tree (Olea europaea) leaf extract (OELE) has important antioxidant and anti-inflammatory properties, supporting its use in human clinical practice (1). A clinical trial and a sub-analysis of it conducted with the amorphous hydrogel EHO-85, containing OELE, for skin ulcer treatments were recently published (2-3). In a new publication, the [...]
The excess of free radicals in the wound environment contributes to its stagnation during the inflammatory phase, favouring hard-to-heal wounds. Oxidative stress negatively affects cells and the extracellular matrix, hindering the healing process. In this study the investigators evaluated the antioxidant and wound-healing properties of a novel multifunctional amorphous hydrogel-containing Olea [...]
Last July 2024, information from the Journal of Wound Management, the official journal of the European Society of Wound Management (EWMA), was published on Linkedin. It contains the results of a study carried out with the EHO-85 hydrogel in anal fissures. At Noventure, we are very pleased to note that [...]
Chronic wounds, especially those that are hard-to-heal, constitute a serious public-health problem. To evaluate the superiority of a hydrogel (EHO-85), containing Olea europaea leaf extract over a standard hydrogel the promotion and/or improvement of healing of difficult-to-heal wounds was compared in a prospective, parallel-group multicenter, randomized, observer-blinded, controlled trial. Non-hospitalized [...]
We are happy to announce the publication of new evidence on the benefit of an antibiotic-free approach (xyloglucan, hibiscus and propolis for oral administration) in the management of uncomplicated urinary tract infections. The objective of this very recent publication in Uro was the evaluation of the efficacy of an oral [...]
A sub-analysis of previous clinical trial (1) conducted with the EHO-85 hydrogel in the treatment of patients with pressure ulcers, venous ulcers or diabetic foot has recently been published in the journal Pharmaceutics (2). On this occasion, the aim was to analyse the ability of the EHO-85 hydrogel to accelerate wound healing [...]
A novel mode of action to promote antibiotic-sparing approach to Recurrent UTIs: Questions and Answers on Clinical Practice1 Consultations for recurrent urinary tract infections (rUTIs) in everyday clinical practice range from 1% to 6% of all medical visits with high social and personal associated costs, such as prescriptions, hospital expenses, [...]
The newer antidiarrheal agents include the mucoprotectants gelatin tannate and xyloglucan. Both were able to attenuate cholera toxin-induced intra-loop water secretion in an experimental study in rats. This supports previous evidence that their mechanism of mucosal protection is closely related to their chemical structures, and involves the ability to form [...]
Let’s celebrate 2022 with a new paper on Utipro® Plus and Utipro® Plus AF!! We are pleased to announce the publication of a meta-analysis in which the benefit of the combination of a mucoprotectant (xyloglucan or an equivalent substance), hibiscus and propolis in the management of uncomplicated urinary tract infections [...]