Dulantha Ulluwishewa, Rachel C. Anderson, Warren C. McNabb, Paul J. Moughan, Jerry M. Wells, and Nicole C. Roy. J. Nutr. May 1, 2011, vol. 141 no. 5 769-776 The human intestinal epithelium is formed by a single layer of epithelial cells that separates the intestinal lumen from the underlying [...]
Allegrini A. & Constantini M. J Gastroint Dig Syst 2012, 2:3. Abstract: Gelatine tannate has been recently licensed as a medical device for the treatment of acute diarrhoea. Gelatine tannate is thought to act locally on the gut wall by forming a protective protein-based film and allowing the precipitation of [...]
Durban Reguera F. et al. Presented as a poster in the congress “Semana de las Enfermedades Digestivas” in Madrid (Spain), June 2007. [...]
De Servi B, et al. Presented at GFHGHP 2012. Presented as oral communication at the 33rd edition of the Congress from the Groupe Francophone d’Hépato-Gastroentérologie et Nutrition Pédiatriques, Nantes (France),March 2012. Abstract: New insights into the mechanism of action of gelatine tannate for acute diarrhoea. Part 2: antibacterial activity. De [...]
Guglietta A. Future Microbiology. Published online: 27 Feb 2017 Urinary tract infections(UTIs) are one of the most common bacterial infections in women, often as a recurrent disease. Uropathogenic Escherichia coli (UPEC) is the most common pathotype of extraintestinal pathogenic E. coli (ExPEC) found among patients with UTI. The human [...]
Norimasa Sawada Pathology International Tight junctions are intercellular junctions adjacent to the apical ends of paracellular spaces. They have two classical functions, the barrier function and the fence function. The former regulates the passage of ions, water and various molecules through paracellular spaces, and is thus related to edema, [...]
Marion M. France, Jerrold R. Turner J Cell Sci 2017 (Journal of Cell Science) Mucosal barriers separate self from non-self and are essential for life. These barriers, which are the first line of defense against external pathogens, are formed by epithelial cells and the substances they secrete. Rather than [...]
Sundar P. Authimoolam and Thomas D. Dziubla Polymers 2016, 8(3), 71 Mucin networks are viscoelastic fibrillar aggregates formed through the complex self-association of biopolymeric glycoprotein chains. The networks form a lubricious, hydrated protective shield along epithelial regions within the human body. The critical role played by mucin networks in [...]
Zihni C1, Mills C1, Matter K1, Balda MS1. Nat Rev Mol Cell Biol. 2016 Sep;17(9):564-80. doi: 10.1038/nrm.2016.80. Epub 2016 Jun 29. Epithelia and endothelia separate different tissue compartments and protect multicellular organisms from the outside world. This requires the formation of tight junctions, selective gates that control paracellular diffusion of [...]
Sara Sattin, Anna Bernard Cell Press, Volume 34, Issue 6, p483–495, June 2016 Microbial adhesion is an essential step in infection and is mediated primarily by protein–carbohydrate interactions. Antagonists of such interactions have become a promising target for anti-adhesive therapy in several infective diseases. Monovalent protein–sugar interactions are often [...]