Szajewska H, Kołodziej M, Łukasik J. Drug development and acute gastrointestinal infections. Expert Opin Investig Drugs. 2017 Dec 26:1-6 Expert Opin Investig Drugs. 2017 Dec 26:1-6. NO ABSTRACT AVAILABLE Mucoprotectans chapter: 4. Mucosal protective agents Clarifying the role of intestinal mucus in reducing inflammation and infection has led to the [...]
Eutamene, Beaufrand Harkat C, Theodorou V. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2018 ABSTRACT Introduction: The intestinal barrier controls the absorption of nutrients and water whilst helping to prevent the entry of toxins and pathogenic micro-organisms from the lumen into the tissues. Deficiencies in the barrier are associated with various [...]
Annamaria Staiano Italian Journal of Pediatrics 2017, 43(Suppl 1): A2 Diarrhoea in children still has a major impact on health-related social costs, affecting approximately 2 billion children younger than 5 years every year, and determining 2 million deaths, mostly in Africa and Asia. [1] According to WHO diarrhea consists in [...]
L. Bueno et al. UEG Journal – United European Gastroenterology Journal, Oct.2013: Vol. 1, Supl. 1; ISSN 2050-6406 (print) ISSN 2050-6414 (online) – Pags A75-A76 Introduction: Gelatine (GEL) stabilised by cross-linking with tannic acid (TA) forms gelatine tannate (GT). GT is approved as medical device for the oral treatment of diarrhoea [...]
Freli V. et al. Presented at GFHGHP 2012. Presented as oral communication at the 33rd edition of the Congress from the Groupe Francophone d’Hépato-Gastroentérologie et Nutrition Pédiatriques in Nantes, France, March 2012. Abstract: New insights into the mechanism of action of gelatine tannate for acute diarrhoea. Part 1: filmforming effect. [...]
In order to further disseminate its proprietary barrier technology, on which the new concept “mucoprotection” is based, and as part of its continuous investment in its products´ reputation, Noventure has just participated in this year´s ESPGHAN Congress, held in Prague. Pediatric gastroenterologists are a key target group for the recommendation [...]
Jess Torres-Herrera, and Gabriel Torres-Ruiz. Current Drug Therapy, 2017, 12, 1-6 Background: Gelatin tannate is bowel selective, safe and effective, and acts locally to form a biofilm. As an adjuvant to oral rehydration solution (ORS), gelatin tannate acts as a mucoprotectant in the management of acute diarrhea in children. Objective: [...]
Soner Sertan Kara, Burcu Volka2, Ibrahim Erten. G-eP-020. ESPGHAN 50th Annual Meeting – Abstracts. May 2017. Pag 114 Objectives and study: Acute gastroenteritis (AGE) is a common cause of morbidity and mortality worldwide. The management of children and infants with viral AGE mainly depends on oral or intravenous hydration, breastfeeding, [...]
Çağan E, Ceylan S, Mengi Ş, Çağan HH. Med Sci Monit. 2017 Apr 27;23:2029-2034. Background: Acute diarrhea is the second most common cause of morbidity and mortality worldwide, especially in children aged ≤3 years. Some drugs (e.g., the mucoprotector gelatin tannate) plus a reduced osmolality oral rehydration solution (ORS) may [...]
Michałek D, Kołodziej M, Konarska Z, Szajewska H. BMJ Open. 2016;6(2):e010530. doi:10.1136/bmjopen-2015-010530. Introduction: Worldwide, acute gastroenteritis in children, usually caused by viruses, leads to considerable morbidity and mortality. The treatment is aimed at preventing and treating dehydration, promoting weight gain after rehydration, and reducing the duration and severity of diarrhoea. [...]