De Servi B et al. Protective barrier properties of Rhinosectan® spray (containing xyloglucan) on an organotypic 3D airway tissue model (MucilAir): results of an in vitro study. Allergy Asthma Clin Immunol. 2017 Aug 10;13:37 Allergy Asthma Clin Immunol. 2017 Aug 10;13:37 Full text free!! Abstract: Background: To evaluate barrier protective properties [...]
M. Lanza1, I. Paterniti1, M. Campolo1 ,G. Casili1 , A. Filippone1,A. Peritore1, S. Cuzzocrea1,2 ,E. Esposito1 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina- Messina, Italy 2Department of Pharmacological and Physiological Science, Saint Louis University, South Grand Blvd St. Louis, Missouri, USA Beneficial effect of the combination [...]
Szajewska H, Kołodziej M, Łukasik J. Drug development and acute gastrointestinal infections. Expert Opin Investig Drugs. 2017 Dec 26:1-6 Expert Opin Investig Drugs. 2017 Dec 26:1-6. NO ABSTRACT AVAILABLE Mucoprotectans chapter: 4. Mucosal protective agents Clarifying the role of intestinal mucus in reducing inflammation and infection has led to the [...]
Eutamene, Beaufrand Harkat C, Theodorou V. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2018 ABSTRACT Introduction: The intestinal barrier controls the absorption of nutrients and water whilst helping to prevent the entry of toxins and pathogenic micro-organisms from the lumen into the tissues. Deficiencies in the barrier are associated with various [...]
Servi B, Ranzini F. Protective efficacy of antidiarrheal agents in a permeability model of Escherichia coli-infected CacoGoblet® cells. Future Microbiol. 2017 Oct 25. Future Microbiol. 2017 Oct 25. Abstract: Aim: To compare the protective efficacy of gelatine tannate/probiotic with other antidiarrheal agents in Escherichia coli-inoculated CacoGoblet® cells. Methods: Four test compounds [...]
Following the publication of the experimental study by Fraile B et al. “Xyloglucan, hibiscus and propolis for the prevention of urinary tract infections: results of in vitro studies.” on Future Microbiology 2017; 12: 721-73 , the authors presented a new communication at the VII International Congress of Histology and Tissue Engineering. Santiago [...]
Annamaria Staiano Italian Journal of Pediatrics 2017, 43(Suppl 1): A2 Diarrhoea in children still has a major impact on health-related social costs, affecting approximately 2 billion children younger than 5 years every year, and determining 2 million deaths, mostly in Africa and Asia. [1] According to WHO diarrhea consists in [...]
Ford et al. N Engl J Med 2017; 376:2566-78 New article in NEJM supports the role of increased intestinal permeability in the pathophysiology of IBS. Increased intestinal permeability and tight junctions alterations trigger an inflammatory reaction which alters visceral neuromuscular function, leading to IBS symptoms like abdominal pain and diarrhea [...]
De Servi B et al. Future Microbiology. Published on line: 29 March 2016 Aim: To evaluate whether Utipro(®), a natural product approved to prevent urinary tract infections, protects intestinal epithelial cells from Escherichia coli adherence/intracellular invasion in vitro. Materials & Methods: Caco-2 and CacoGoblet(TM) cells were treated with Utipro (1.5 [...]
L. Bueno et al. UEG Journal – United European Gastroenterology Journal, Oct.2013: Vol. 1, Supl. 1; ISSN 2050-6406 (print) ISSN 2050-6414 (online) – Pags A75-A76 Introduction: Gelatine (GEL) stabilised by cross-linking with tannic acid (TA) forms gelatine tannate (GT). GT is approved as medical device for the oral treatment of diarrhoea [...]