New insights into the mechanism of action of gelatine tannate for acute diarrhoea. Part 1: film-forming effect.

Freli V. et al. Presented at GFHGHP 2012. Presented as oral communication at the 33rd edition of the Congress from the Groupe Francophone d’Hépato-Gastroentérologie et Nutrition Pédiatriques in Nantes, France, March 2012. Abstract: New insights into the mechanism of action of gelatine tannate for acute diarrhoea. Part 1: filmforming effect. [...]

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Intestinal goblet cells and mucins in health and disease: recent insights and progress.

Kim YS, Ho SB. Curr Gastroenterol Rep. 2010 Oct;12(5):319-30   The mucus layer coating the gastrointestinal tract is the front line of innate host defense, largely because of the secretory products of intestinal goblet cells. Goblet cells synthesize secretory mucin glycoproteins (MUC2) and bioactive molecules such as epithelial membrane-bound mucins (MUC1, [...]

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Gelatin Tannate: A Selective Biofilm-forming, Gut Mucoprotectant for Acute Gastroenteritis in Children. A Short Narrative Review.

Jess Torres-Herrera, and Gabriel Torres-Ruiz. Current Drug Therapy, 2017, 12, 1-6 Background: Gelatin tannate is bowel selective, safe and effective, and acts locally to form a biofilm. As an adjuvant to oral rehydration solution (ORS), gelatin tannate acts as a mucoprotectant in the management of acute diarrhea in children. Objective: [...]

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Scientific publicationRegulation of tight junctions in upper airway epithelium.

Takashi Kojima, Mitsuru Go, Ken-ichi Takano, Makoto Kurose, Tsuyoshi Ohkuni, Jun-ichi Koizumi, Ryuta Kamekura, Noriko Ogasawara, Tomoyuki Masaki, Jun Fuchimoto, Kazufumi Obata, Satoshi Hirakawa, Kazuaki Nomura, Takashi Keira, Ryou Miyata, Nobuhiro Fujii, Hiroyuki Tsutsumi, Tetsuo Himi and Norimasa Sawada   BioMed Research International, Volume 2013 (2013), Article ID 947072, 11 [...]

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Xyloglucan for the treatment of acute gastroenteritis in children: results of a randomized, controlled, clinical trial

Catalin Pleasea Condratovici,  Vladimir C. Bacârea, Núria Piqué. Gastroenterology Research and Practice. April 2016 Background: Xyloglucan, a film-forming agent, improves intestinal mucosa resistance to pathologic damage. The efficacy, safety, and time of onset of the antidiarrheal effect of xyloglucan were assessed in children with acute gastroenteritis receiving oral rehydration solution [...]

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Evaluation of Gelatin Tannate Against Symptoms of Acute Diarrhea in Pediatric Patients.

Çağan E, Ceylan S, Mengi Ş, Çağan HH. Med Sci Monit. 2017 Apr 27;23:2029-2034. Background: Acute diarrhea is the second most common cause of morbidity and mortality worldwide, especially in children aged ≤3 years. Some drugs (e.g., the mucoprotector gelatin tannate) plus a reduced osmolality oral rehydration solution (ORS) may [...]

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