New publication on good results with EHO-85 hydrogel compared to products commonly used in wound healing.

Olive tree (Olea europaea) leaf extract (OELE) has important antioxidant and anti-inflammatory properties, supporting its use in human clinical practice (1). A clinical trial and a sub-analysis of it conducted with the amorphous hydrogel EHO-85, containing OELE, for skin ulcer treatments were recently published (2-3). In a new publication, the effect of EHO-85 on healing was evaluated in comparison with treatments containing Centella asiatica, hyaluronic acid, or dexpanthenol in a rat model. The speed of wound closure and histological parameters after seven and 14 days were analysed. All treatments accelerated wound closure, but there were differences among them. EHO-85 also promoted epithelialization and reduced vascularization. After 14 days, wounds treated with EHO-85 showed less inflammation and higher levels of collagen in the extracellular matrix. This indicates a higher degree of maturity in the regenerated tissue. In conclusion, the effect of EHO-85 on healing was equal to or superior to that of other treatments routinely used in human clinical practice (1).

(1) Torrecillas-Baena B et al. Comparative Study of the Efficacy of EHO-85, a Hydrogel

Containing Olive Tree (Olea europaea) Leaf Extract, in Skin Wound Healing. Int. J. Mol. Sci. 2023, 24, 13328. https://doi.org/10.3390/ijms241713328

(2) Verdú-Soriano J et al. J. Clin. Med. 2022, 11, 1260. https://doi.org/10.3390/jcm11051260

(3) Verdú-Soriano J et al. Pharmaceutics 2023, 15, 1925. https://doi.org/10.3390/pharmaceutics15071925