Gelatin tannate ameliorates acute colitis in mice by reinforcing mucus layer and modulating gut microbiota composition: Emerging role for ‘gut barrier protectors’ in IBD?

United European Gastroenterology Journal 2014, Vol. 2(2) 113–122

Background:

Gelatin tannate, a gelatin powder containing tannic acids, is commonly employed as an intestinal astringent. Neither information nor animal model exist to confirm its efficacy or unravel mechanisms of action.

Objective:

To evaluate the action of gelatin tannate in murine dextran sodium sulphate (DSS)-induced acute colitis.

Xyloglucan for the treatment of acute diarrhea: results of a randomized, controlled, open-label, parallel group, multicentre, national clinical trial.

BMC Gastroenterology (2015) 15:153



Background:

There is a strong rationale for the use of agents with film-forming protective properties, like xyloglucan, for the treatment of acute diarrhea. However, few data from clinical trials are available.

XILAPLUS® AF

XILAPLUS® AF:

The medical device is intended to restore the physiological functions of the intestinal walls, specifically formulated for the control and reduction of the symptoms related to diarrheal events of different aetiologies, such as abdominal tension and frequent emission of faeces.

The medical device acts by forming a film which protects the intestinal mucosa, reducing the frequency and duration of diarrhoea episodes. 

CE 0476

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Nicolas Foucart

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