The excess of free radicals in the wound environment contributes to its stagnation during the inflammatory phase, favouring hard-to-heal wounds. Oxidative stress negatively affects cells and the extracellular matrix, hindering the healing process. In this study the investigators evaluated the antioxidant and wound-healing properties of a novel multifunctional amorphous hydrogel-containing Olea europaea leaf extract (OELE) in different experimental  models.