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Regulation of tight junctions in upper airway epithelium.

Takashi Kojima, Mitsuru Go, Ken-ichi Takano, Makoto Kurose, Tsuyoshi Ohkuni, Jun-ichi Koizumi, Ryuta Kamekura, Noriko Ogasawara, Tomoyuki Masaki, Jun Fuchimoto, Kazufumi Obata, Satoshi Hirakawa, Kazuaki Nomura, Takashi Keira, Ryou Miyata, Nobuhiro Fujii,

Rhinosectan’s mode of action has been studied in experimental models with nasal mucosa cells. In these models, the presence of xyloglucan prevents the harmful action of substances known to damage the architecture of the cells. This is thanks to the protective barrier effect that comes from the mucoadhesivity of this polymer (1).

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The mucosal barrier at a glance

Marion M. France, Jerrold R. Turner

J Cell Sci 2017 (Journal of Cell Science) Mucosal barriers separate self from non-self and are essential for life. These barriers, which are the first line of defense against external pathogens, are formed by epithelial cells and the substances they secrete.Rather than an absolute barrier,...

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2021, Mar 01

euroPLX 75 Lisbon

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